Foundations in Microbiology by
Talaro/Chess: Foundations in Microbiology is an allied health microbiology text for non-science majors with a taxonomic approach to the disease chapters. It offers an engaging and accessible writing style through the use of tools such as case studies and analogies to thoroughly explain difficult microbiology concepts. We are so excited to offer a robust learning program with student- focused learning activities, allowing the student to manage their learning while you easily manage their assessment. Detailed reports show how your assignments measure various learning objectives from the book (or input your own ), levels of Bloom's Taxonomy or other categories, and how your students are doing. The Talaro Learning program will save you time while improving your students success in this course.
A Planet of Viruses by
Viruses are the smallest living things known to science, yet they hold the entire planet in their sway. We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground. This fascinating book explores the hidden world of viruses--a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine's award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world's oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine. The New York Times Book Review calls Carl Zimmer "as fine a science essayist as we have." A Planet of Viruses is sure to please his many fans and further enhance his reputation as one of America's most respected and admired science journalists.
RNA by
In RNA: Life's Indispensable Molecule, Jim Darnell provides a comprehensive and captivating account of RNA research, illuminated by his own life-long and celebrated engagement in the field. Darnell describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA--how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, and with the clarity expected from an accomplished textbook author, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up, and will particularly appeal to active investigators in RNA biology, educators of molecular biology and biochemistry, and science historians.
A Brief History of Creation by
How did life begin? It is perhaps the most important question science has ever asked. Over the centuries, the search for an answer has been entwined with some of science’s most revolutionary advances including van Leeuwenhoek’s microscope, Darwin’s theory of evolution, and Crick and Watson’s unveiling of DNA. Now, in an age of genetic engineering and space exploration, some scientists believe they are on the verge of creating life from nonliving elements and that our knowledge of the potential for life on other planets is ever-expanding. In the midst of these exciting developments, A Brief History of Creation provides an essential and illuminating history of Western science, tracing the trials and triumphs of the iconoclastic scientists who have sought to uncover the mystery of how life first came to be. Authors Bill Mesler and H. James Cleaves II examine historical discoveries in the context of philosophical debates, political change, and our evolving understanding of the complexity of biology. The story they tell is rooted in metaphysical arguments, in a changing understanding of the age of the Earth, and even in the politics of the Cold War. It has involved exploration into the inner recesses of our cells and scientific journeys to the farthest reaches of outer space. This elegantly written narrative culminates in an analysis of modern models for life’s genesis, such as the possibility that some of the earliest life was composed of little more than RNA, and that life arose around deep-sea hydrothermal vents or even on other planets, only to be carried to the Earth on meteorites. Can we ever conclusively prove how life began? A Brief History of Creation is a fascinating exploration not only of the origin-of-life question but of the very nature of scientific objectivity and the process of scientific discovery.
Planet of Microbes by
We live in a time of unprecedented scientific knowledge about the origins of life on Earth. But if we want to grasp the big picture, we have to start small--very small. That's because the real heroes of the story of life on Earth are microbes, the tiny living organisms we cannot see with the naked eye. Microbes were Earth's first lifeforms, early anaerobic inhabitants that created the air we breathe. Today they live, invisible and seemingly invincible, in every corner of the planet, from Yellowstone's scalding hot springs to Antarctic mountaintops to inside our very bodies--more than a hundred trillion of them. Don't be alarmed though: many microbes are allies in achieving our--to say nothing of our planet's--health. In Planet of Microbes, Ted Anton takes readers through the most recent discoveries about microbes, revealing their unexpected potential to reshape the future of the planet. For years, we knew little about these invisible invaders, considering them as little more than our enemies in our fight against infectious disease. But the more we learn about microbes, the more it's become clear that our very lives depend on them. They may also hold the answers to some of science's most pressing problems, including how to combat a warming planet, clean up the environment, and help the body fight off a wide variety of diseases. Anton has spent years interviewing and working with the determined scientists who hope to harness the work of microbes, and he breaks down the science while also sharing incredible behind-the-scenes stories of the research taking place everywhere from microbreweries to Mars. The world's tiniest organisms were here more than three billion years before us. We live in their world, and Planet of Microbes at last gives these unsung heroes the recognition they deserve.
The Molecules of Life : DNA, RNA, and Proteins by
Thanks to new technology, scientists are able to observe organic molecules as they work together in the cell and in “molecular machines,” as well as how they build tissues, organs, and whole organisms. Understanding how these levels of structure work together not only answers fundamental questions about life, but it also gives hope for finding a cure for some of the major diseases that plague our species. Finding cures to genetic diseases requires a deep understanding of the mechanics of single molecules. The Molecules of Life explains how the chemistry and physics of organic molecules drive processes within cells and permit the construction of amazingly complex plants and animals. Describing some of the basic concepts needed to understand the field and discussing the methods used to explore the structures and behavior of DNA, RNA, and proteins, this book is devoted to stories about how these molecules carry out the business of life. The Molecules of Life shows how and why scientists study biological molecules, including how they are built, how they interact with each other, and what roles they play in the lives of cells and organisms. Chapters include: The Physics and Chemistry of Life: Basic Principles and Methods How the Cell Stores and Uses Information Communication Between and Inside Cells Traffic and Cell Architecture Molecules of Immunity, Health, and Disease.
RNAi by
Martin Latterich covers the basic concepts and mechanisms of RNAi, transfection of cells with siRNAs, the design and validation of reagents, techniques in different organisms, large-scale RNAi screening, applications in drug discovery, and potential uses as a therapeutic agent.
DNA and RNA Modification Enzymes by
This volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers fundamental principles as well as up to date information on recent advances in the field (up to end 2008). They ended by a short 'conclusion and future prospect' section and an exhaustive list of 35 to up to 257 references (in average 87). Contributors are geneticists, structural enzymologists and molecular biologists working at the forefront of this exciting, fast-moving and diverse field of researches. This book will be a major interest to PhD students and University teachers alike. It will also serve as an invaluable reference tool for new researchers in the field, as well as for specialists of RNA modification enzymes generally not well informed about what is going on in similar processes acting on DNA and vice-versa for specialists of the DNA modification-editing and repair processes usually not much acquainted with what is going on in the RNA maturation field. The book is subdivided into 41 chapters (740 pages). The common links between them are mainly the enzymatic aspects of the different modification-editing and repair machineries: structural, mechanistic, functional and evolutionary aspects. It starts with two general and historical overview of the discovery of modified nucleosides in DNA and RNA and corresponding modification-editing enzymes. Then follows eleven chapters on DNA modification and editing (mechanistic and functional aspects). Two additional chapters cover problems related to DNA/RNA repair and base editing by C-to-U deaminases, followed by three chapters on RNA editing by C-to-U and A-to-I type of deamination. Discussions about interplay between DNA and RNA modifications and the emergence of DNA are covered in two independent chapters, followed by twenty chapters on different but complementary aspects of RNA modification enzymes and their cellular implications. The last chapter concerns the description of the present state-of-the art for incorporating modified nucleosides by in vitro chemical synthesis. At the end of the book, six appendicies give useful details on modified nucleosides, modification-editing enzymes and nucleosides analogs. This information is usually difficult to obtain from current scientific literature.
