Biology II Essentials by
REA’s Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Biology II includes stimulus receptors in animals, nervous systems, locomotion, elements of behavior, reproduction of cells and organisms, genetic inheritance, embryonic development, evolution, and ecology.
Biomarker Tests for Molecularly Targeted Therapies by
Every patient is unique, and the evolving field of precision medicine aims to ensure the delivery of the right treatment to the right patient at the right time. In an era of rapid advances in biomedicine and enhanced understanding of the genetic basis of disease, health care providers increasingly have access to advanced technologies that may identify molecular variations specific to an individual patient, which subsequently can be targeted for treatment. Known as biomarker tests for molecularly targeted therapies, these complex tests have the potential to enable the selection of the most beneficial treatment (and also to identify treatments that may be harmful or ineffective) for the molecular underpinnings of an individual patient (TM)s disease. Such tests are key to unlocking the promise of precision medicine. Biomarker tests for molecularly targeted therapies represent a crucial area of focus for developing methods that could later be applicable to other areas of precision medicine. The appropriate regulatory oversight of these tests is required to ensure that they are accurate, reliable, properly validated, and appropriately implemented in clinical practice. Moreover, common evidentiary standards for assessing the beneficial impact of biomarker-guided therapy selection on patient outcomes, as well as the effective collection and sharing of information related to those outcomes, are urgently needed to better inform clinical decision making. Biomarker Tests of Molecularly Targeted Therapies examines opportunities for and challenges to the use of biomarker tests to select optimal therapy and offers recommendations to accelerate progress in this field. This report explores regulatory issues, reimbursement issues, and clinical practice issues related to the clinical development and use of biomarker tests for targeting therapies to patients. Properly validated, appropriately implemented biomarker tests hold the potential to enhance patient care and improve outcomes, and therefore addressing the challenges facing such tests is critical.
Biomarkers by
This book provides a survey of biochemical, physiological and histological biomarkers of environmental stress, along with evaluations of the strengths and weaknesses of various techniques for different applications. It features in-depth coverage of such topics as DNA adducts, acetylcholinesterase, ATP, endocrine mechanisms, blood chemistry, histopathological biomarkers, stress proteins, foreign and endogenous metabolites, metallothioneins, to name only a few. The book will be especially useful to toxicologists, biochemists, histologists, immunologists, risk analysis specialists, environmental managers, regulators, environmental scientists and engineers.
Clinical Microbiology for Diagnostic Laboratory Scientists by
A modern, evaluative, and integrative approach to diagnostic microbiology encouraging problem-solving in the clinical laboratory context through the use of examples to illustrate clinical and diagnostic issues Clinical Microbiology for Diagnostic Laboratory Scientists is designed to encourage readers to develop a way of thinking that can be applied to any diagnostic scenario in microbiology. Through consideration of a selected range of infections caused by pathogenic bacteria, viruses, fungi, protozoa, and helminths, the book encourages readers to explore connections between the available information about clinical symptoms, pathogenesis of infections, and the approaches used in laboratory diagnosis, in order to develop new insights. The book begins with an introductory chapter that outlines the scope of clinical diagnostic microbiology and the key areas for the laboratory scientist to be aware of. The subsequent six chapters review a type of infection in depth, using particular pathogenic microorganisms to illustrate salient points. At the end of each chapter there are three exercises related to management of a diagnostic service and assessing the suitability of test methods to specific contexts. There are no right or wrong answers to these, but the reader can discuss them with their laboratory colleagues or university tutor. Makes extensive use of published research in the form of journal articles, publically available epidemiological data, professional guidelines, and specialist websites Stimulates the reader in critical appraisal of published evidence and encourages problem-solving in the laboratory Outlines the scope of clinical diagnostic microbiology and the key areas for the laboratory scientist to be aware of Considers topics relevant to professional scientists working in the area of diagnostic microbiology Clinical Microbiology for Diagnostic Laboratory Scientists is ideal for post graduate scientists intending to pursue careers in diagnostic clinical microbiology and for biomedical scientists, clinical scientists, and full time students studying for upper level qualifications in biomedical science, microbiology, or virology.
Textbook of Histology by
Thoroughly updated to reflect all of the latest concepts and advances in the field, this concise, extensively illustrated text presents the basic science and clinical application of cellular and molecular biology. Functioning as a combined text and atlas, it is essentially two books for the price of one providing a comprehensive, visually engaging histology education from the ground up. Illustrations, tables, PowerPointT presentations, chapter summaries and multiple choice questions facilitate comprehension of concepts, and clinical correlations underscore the practical relevance of the material. Superb illustrations-including photomicrographs, electron micrographs, schematic diagrams and drawings-provide a visual grasp and easier retention of difficult concepts. Online PowerPointT slides, prepared by the author, offer a convenient way to review the most essential information from the text. Clinical correlations throughout the text demonstrate clinical applications and reinforce the idea that histology is pertinent not only to pathology and physiology, but in fact comprises one of the essential bases of clinical practice. New! "Pathological Considerations" section at the end of each chapter. Helpful tables provide an at-a-glance summary statement of key points. Bolded key terms, bulleted lists and chapter summaries emphasize the "need to know" information in every chapter. A combination of USMLE-style questions and image based questions in each chapter. Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Lever's Histopathology of the Skin by
Rely on Lever's for more accurate, more efficient diagnoses! Continuously in publication for more than 65 years, Lever's Histopathology of the Skin remains your authoritative source for comprehensive coverage of those skin diseases in which histopathology plays an important role in diagnosis. This edition maintains the proven, clinicopathologic classification of cutaneous disease while incorporating a "primer" on pattern-algorithm diagnosis. More than 1800 full-color illustrations, including photomicrographs and clinical photographs, help you visualize and make the most of the clinical diagnostic process.Key Features New Clinical Summaries for most disease entities provide a concise clinical review before presenting histologic features. New Principles of Management section summarizes today's complex treatment modalities in one convenient place. Ultrastructural, immunohistochemical, and molecular techniques are discussed where they have value in identifying particular diseases. Updated chapter dedicated to algorithmic classification of skin diseases according to histologic pattern features helps you develop a differential diagnosis for unknown cases . Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: Complete content with enhanced navigation Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use
Atlas of Gynecologic Cytopathology with Histopathologic Correlations by
This Atlas offers concrete diagnostic guidance for anatomic pathologists to accurately identify gynecologic tract disease using PAP tests. It not only illustrates the cytomorphology of cervical specimens, but also presents and contrasts common problem areas that can lead to erroneous interpretation. Clearly and concisely written by leaders in the field, this volume is a practical desk reference for all facets of the diagnostically challenging area of gynecological tract exfoliative cytopathology. The Atlas features nearly 500 carefully selected high-resolution color images detailing important aspects of gynecologic tract disease. Additionally, the book√ s images of the histopathology and gross characteristics of lesions provide morphologic correlations that will be relevant to cytopathologists and surgical pathologists alike. To provide a broader, more enriching perspective, the Atlas features a special chapter on the colposcopic characteristics of cervical lesions to provide a differential diagnosis through the eyes of an experienced gynecologist. It also reviews the updated management guidelines of the American Society for Colposcopy and Cervical Pathology (ASCCP), providing a multidisciplinary approach to enhance the reader√ s understanding of how cytopathology, histopathology, and colposcopic information together create a powerful tool for the prevention and early detection of cervical dysplasia and cancer. Key Features: Provides practical, expert diagnostic guidance for the full range of gynecologic cytopathology Illuminates common diagnostic pitfalls Presents nearly 500 high-resolution color images Includes colposcopic-pathologic correlations from an expert gynecologist Reviews updated ASCCP guidelines emphasizing a multidisciplinary management approach
Atlas of Pulmonary Cytopathology by
Atlas of Pulmonary Cytopathology With Histopathologic Correlations offers concrete diagnostic guidance for anatomic pathologists to accurately identify pulmonary disease using exfoliative and fine needle aspiration techniques. It not only illustrates the classic cytomorphology of common lung lesions, but also presents and contrasts important problem areas that can lead to erroneous interpretation. Clearly and concisely written by leaders in the field, this volume is a practical desk reference for all facets of the diagnostically challenging areas of pulmonary cytopathology. The Atlas features more than 500 carefully selected high-resolution images detailing important aspects of the full range of lung diseases and conditions including infections, reactive lesions, benign neoplasms, and malignant tumors such as adenocarcinoma, squamous cell carcinoma, neuroendocrine tumors, malignant mesothelioma, and metastatic tumors. Additionally, the book contains images of the histopathology and gross characteristics of certain lesions to provide morphologic correlations that will be relevant to cytopathologists and surgical pathologists alike. To provide a broader, more enriching perspective, the Atlas features a special chapter on the radiologic characteristics of lung lesions to provide a differential diagnosis through the eyes of an experienced radiologist. This multidisciplinary approach enhances the reader's understanding of how cytopathology, histopathology, and radiologic information together create a powerful tool for understanding the neoplastic, reactive, and infectious disease of the lower respiratory tract. KEY FEATURES Provides practical, expert diagnostic guidance for the full range of pulmonary cytopathologyDiscusses common diagnostic pitfalls and interpretive errors encountered in respiratory tract specimensCorrelates cytologic features with those seen on histologyPresents more than 500 high-resolution imagesIncludes radiologic-pathologic correlations from an expert radiologist
Immunohistochemistry and Immunocytochemistry by
Immunohistochemistry and immunocytochemistry are invaluable tools for the visualization of tissue and cellular antigens in diagnostic and biological research environments. The need to obtain accurate, reliable and reproducible results is paramount. It is with this fundamental aim in mind that we have compiled Immunohistochemistry: Essential Methods. We have achieved this by examining each aspect of immunochemistry in turn, with each chapter including detailed information regarding the subject matter in question. Each chapter is written by an expert in their field and includes protocols that are typically used in their own research. Subjects covered are, amongst others, antibodies and their production; selection of reporter labels; immunochemical staining methods and experimental design (both using single and multiple reporter labels); quality assurance; automated immunochemistry; confocal microscopy and electron microscopy. In addition, benefits and limitations of each approach are discussed within the chapters.
Digital Pathology by
Digital Pathology: Historical Perspectives, Current Concepts & Future Applications provides the authoritative text in the digital pathology domain by combining the established expertise of leaders in this diverse arena with practical applications of this transformative platform while harnessing a content rich, interactive format. In detailing a cohesive narrative from a broad, global perspective the lessons learned from the past, the obstacles to digital pathology adoption that have been overcome and the challenges that remain for full realization of the potential that computational analysis affords, this text provides readers with the latest in where the field is heading as it seeks to unlock the potential of digital pathology by leveraging cutting edge technologies and innovative tools. Digital Pathology: Historical Perspectives, Current Concepts & Future Applications will be of great value to Pathologists including Translational Researchers and Informaticists, Pathology Trainees including Residents and Informatics Fellows, Healthcare CMIOs and CIOs, Bioimaging Engineers and Computer Vision Scientists, as well as Laboratory Information Technologists.
Molecular Pathology and the Dynamics of Disease by
Molecular Pathology and the Dynamics of Disease bridges the basic science of, and primary clinical literature on, human disease. Topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. As new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective. Assimilates theoretical knowledge with practical lab work Provides a needed clinical perspective, along with research and theory Highlights the impact of basic science on the practice of medicine
Lever's Histopathology of the Skin by
Rely on Lever's for more accurate, more efficient diagnoses! Continuously in publication for more than 65 years, Lever's Histopathology of the Skin remains your authoritative source for comprehensive coverage of those skin diseases in which histopathology plays an important role in diagnosis. This edition maintains the proven, clinicopathologic classification of cutaneous disease while incorporating a "primer" on pattern-algorithm diagnosis. More than 1800 full-color illustrations, including photomicrographs and clinical photographs, help you visualize and make the most of the clinical diagnostic process. Key Features New Clinical Summaries for most disease entities provide a concise clinical review before presenting histologic features. New Principles of Management section summarizes today's complex treatment modalities in one convenient place. Ultrastructural, immunohistochemical, and molecular techniques are discussed where they have value in identifying particular diseases. Updated chapter dedicated to algorithmic classification of skin diseases according to histologic pattern features helps you develop a differential diagnosis for unknown cases. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: Complete content with enhanced navigation Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use
Mohs Micrographic Surgery by 
Scanning Transmission Electron Microscopy of Nanomaterials by
The basics, present status and future prospects of high-resolution scanning transmission electron microscopy (STEM) are described in the form of a textbook for advanced undergraduates and graduate students. This volume covers recent achievements in the field of STEM obtained with advanced technologies such as spherical aberration correction, monochromator, high-sensitivity electron energy loss spectroscopy and the software of image mapping. The future prospects chapter also deals with z-slice imaging and confocal STEM for 3D analysis of nanostructured materials.