BASICS ABOUT PLASTICS
NATURAL POLYMERS |
SYNTHETIC POLYMERS |
Cotton / Silk
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Rubber (elastomers) |
DNA |
Polyvinyl chloride (PVC) |
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Polyesters (PE) |
Images for Cellulose Scaffolding
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HDPE - High Density Polyethylene |
Powerpoint Slide images for infograph
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Polyethylene (Low Density) LDPE |
Starch
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A repository of nucleic acid crystal structure data, the NDB currently contains over 7100 structures.
A product of the Research Collaboratory for Structural Infomatics, the PDB provides a variety of tools and resources for studying the structures of biological macromolecules and their relationships to sequence, function, and disease. The online PDB archive is a repository for the coordinates and related information for more than 97,000 structures, including proteins, nucleic acids and large macromolecular complexes that have been determined using X-ray crystallography, NMR and electron microscopy techniques.
The PDB requires Java and JMol for structure viewing.
A macromolecule is any very large molecule, usually with a diameter ranging from about 1-1000 nanometers.
There are two types: Natural and synthetic. Plastic, resins and many synthetic fibres (e.g. nylon and cotton), rubbers and the biollogically important carbohydrates, proteins and nucleic acids, are among many substances that are made up of macromolecular units.
All of these macromolecules have significance in the modern world as their chemical structure significantly effects their properties and therefore uses/functions.
Above: Structure of rubber
Organic molecules - contain Carbon atoms. They are found in all living things. The simplest organic molecules are Hydrocarbons - consist of only carbon and hydrogen.
Prefix Suffix Meth - 1 carbon atom - ane No double bonds Eth - 2 carbon atoms Prop - 3 carbon atoms - ene At least 1 double bond But - 4 carbon atoms Pent - 5 carbon atoms Hex - 6 carbon atoms
Isomers
Isomers are compounds with the same molecular formula, but different structural formulas.
a) Structural isomers - vary in the arrangement of their atoms
b) Geometric isomers - differ around the atoms in a double bond
c) Enantiomers - are molecules that are mirror-images of each other
Different isomers have different effects on the body eg Ibuprofen, Prozac, Thalidomide
Functional groups
Chemical properties of molecules depend on their functional groups (atoms on the outside of the molecule ).
Functional Structure Example Comments group Hydroxyl - OH Sugars Dissolve in water Carboxyl - COOH Fatty acids Are acid Amino - NH2 Proteins Are basic ( alkali) Phosphate - PO4 DNA Dissolve & are acid
Macromolecules : very large molecules, made of hundreds, or thousands, of atoms. Most are polymers : large molecules made of similar, small monomers joined together
Hydrolysis : a chemical reaction that breaks polymers into monomers eg digestion
Condensation synthesis : a chemical reaction that joins monomers together by removing water.
There are 4 types of macromolecule in living things : carbohydrates, lipids, proteins and nucleic acids.
1). Carbohydrates
Carbohydrates contain only C , H and O. They are made of simple sugars called monosaccharides such as glucose (C6H12O6) and glyceraldehyde (C3H6O3). Monosaccharides dissolve in water.
Disaccharides consist of 2 monosaccharides joined by condensation synthesis such as maltose or brewing sugar (2 glucose) and sucrose or table sugar (glucose + fructose . Monosaccharides and some disaccharides react with Benedicts reagent.
Polysaccharides are made of many monosaccharides, such as :
B) Phospholipids
Phospholipids are made of glycerol, 2 fatty acids and phosphate. Part of the molecule is hydrophobic, part is hydrophilic.
Phospholipids make up most of the cell membrane.
C) Waxes
Waxes consist of a fatty acid joined to an alcohol.They are used for waterproofing in plants (and some animals).
D) Steroids
Steroids are made of 4 rings of carbon. They form sex hormones eg estrogen, testosterone. Animals often need small amounts in their diet eg cholesterol. Drugs in world athletics. High levels of steroids can damage the brain.
3). Proteins
Proteins contain C , H , O and N. They are made of amino acids joined together with a peptide bond. There are 20 different amino acids (do not learn the names). The order of amino acids in a protein is important (see sickle cell anemia below).
Primary structure : the order of amino acids
Secondary structure : the protein folds, and is held by hydrogen bonds
Tertiary structure : covalent or ionic bonds between different side chains of the protein.
Sickle cell anemia : an often fatal genetic disease caused by one amino acid in the wrong place in the protein hemoglobin.
Proteins are unusual because their shape is mainly affected by hydrogen bonds which are weak. This means that if a protein is heated it denatures : the shape changes. For example if you boil an egg (which contains lots of protein) it changes from a raw egg to a cooked egg because the proteins are denatured. This denaturing will usually kill a cell. Proteins are found in cell membranes, blood, hair, enzymes and muscles.
4). Nucleic acids
Nucleic acids contain C , H , O , N and P. They are made of nucleotides, (phosphate, sugar and base)
DNA (Deoxyribonucleic acid) DNA has deoxyribose as the sugar. It has 4 bases :
Adenine Thymine Guanine CytosineDNA bases pair up and join with hydrogen bonds to form a double helix. The code on DNA carries information the cell needs to make proteins (the primary structure).